SARS-CoV-2 vaccination response analyzed among UK healthcare workers with ethnic variations.

A study on UK healthcare workers compared cellular and humoral immune responses to SARS-CoV-2 vaccination by ethnic group. Results showed that, in an infection naïve cohort, both humoral and cellular immune responses were stronger in South Asian healthcare workers than in White healthcare workers. The differences were most pronounced in the early period following vaccination. The study was funded by UK Research and Innovation and conducted using baseline data from two immunological cohort studies in Leicester, UK. Further research is needed to understand the underlying mechanisms, whether differences persist with further exposure to the vaccine or virus, and the potential impact on vaccine effectiveness.